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The pipeline

From collision to brief

Eleven steps. Two pipelines: L0 generates the hypotheses; the post-🔥 stage validates the strongest ones in depth.

🎲

Collision

~100 collisions/day

500 scientific domains. A random draw collides two of them.

🚪

Filter

30-60% pass

A filter rejects trivial or already-explored pairs.

🧩

Synthesis

~70% bridges

An LLM generates a causal bridge between the two domains.

⚔️

Critique

5 scores produced

A devil's advocate and an angel's advocate debate.

🎯

Selection

Top 15%

Top 15% retained on composite score.

⚖️

Review

~15-20% 🔥

Calibrated verdict: rejected / interesting / to test 🔥.

📚

Literature grounding

Post 🔥5+ references

8-12 Semantic Scholar queries. Zero hallucination — every DOI is verified.

🔬

Hypothesis sharpening

Post 🔥

Rigorous formulation with variables, quantitative predictions, H0, statistical tests.

🧪

Protocol

Post 🔥

Three phases: in silico (€0-2k) → minimal (€2-15k) → full (€15-200k).

🎭

Panel (5 reviewers)

Post 🔥

Methodologist, domain expert, devil's advocate, industry reviewer, funding strategist.

📄

Research brief

Post 🔥

Publication-ready document of 4-6 pages. Markdown + JSON.

The funnel in numbers (100 typical collisions)

100
Collisions
30-60
Pass the filter
~20
Hypotheses
~3
Shortlisted
~0.5
🔥 briefs

Across SPORE: 4,425 collisions explored 41 briefs published.

Philosophy

Three non-negotiable principles

🤝

SPORE proposes; humans dispose

The system generates and validates; it does not replace human judgement. Every brief is an invitation to think, not a conclusion.

🎯

Zero bibliographic hallucination

Every reference is verified through Semantic Scholar. If a DOI does not resolve, it is dropped. Citations are the foundation.

🎭

Five reviewers, five perspectives

Methodologist, domain expert, devil's advocate, industry reviewer, funding strategist. No blind spot. Every doubt is voiced.

For a detailed account of how each metric is computed — including its limits — see the Methodology page.

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