in silico
Phase 1 : In Silico Validation: Computational Feasibility & Sensitivity Analysis
- Objectif
- To computationally falsify the core mechanism (RPN-based optimization outperforms random placement) using synthetic data, and to determine the sensitivity of the optimization to expert panel variability and failure mode spatial assumptions before any physical experiment.
- Coût estimé
- €500-1,500 (computing time & software licenses, if any)
- Durée estimée
- 4-6 weeks
- Critères de réussite
- Mean detection time difference (FMEA - Random) · ≥ 15 days (as per Prediction 1) · (From 100 Monte Carlo simulations; compute mean and 95% CI via bootstrap (10,000 resamples))
- Inter-panel CV of RPN scores for top 10 failure modes · < 30% (as per Prediction 2) · (Compute CV = (σ / μ) × 100% for each failure mode; average across modes)
- Sensor count reduction to achieve POD ≥ 0.80 · ≥ 25% reduction (e.g., from 16 to 12 sensors) (as per Prediction 3) · (ROC analysis on detection times; find N where POD first exceeds 0.80 for each network design)
- On continue si
- All three success criteria met in synthetic simulations (mean detection time difference ≥ 15 days, CV < 30%, sensor reduction ≥ 25%)
- On arrête si
- Any criterion fails by >20% (e.g., detection time difference < 12 days, CV > 36%, sensor reduction < 20%)
- On réoriente si
- Detection time difference is 12-15 days OR CV is 30-36% OR sensor reduction is 20-25% — then refine expert panel simulation (increase panel size to n=7) and re-run Phase 1 before proceeding
- Risques
- Synthetic data assumptions (Gaussian footprints, stationary failure modes) may not reflect real lake dynamics, leading to over-optimistic resultsProbabilité : mediumParade : Add a “stress test” scenario where failure mode footprints are non-stationary (drifting centroids) and DO decline is non-linear (sigmoidal). If results degrade, adjust Phase 2 design to include real lake data.
- Computational cost of Monte Carlo simulations may exceed workstation capacityProbabilité : lowParade : Use cloud computing (AWS EC2 spot instances, ~€0.04/hour) or Google Colab Pro for GPU-accelerated simulations. Budget €100 for cloud credits.
- Expert panel simulation may not capture real human variability (anchoring bias, scale interpretation)Probabilité : mediumParade : Calibrate synthetic panels using published FMEA inter-rater reliability data (e.g., from healthcare FMEA studies). If CV > 30% persists, plan for larger expert panels (n=10) in Phase 2.